CD27 Human-CD Antigens

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CD27 Human

Qty


Total
$65
Catalog #
PRPS-1220
Size
Description
CD27 Human Recombinant produced in E. coli is a single polypeptide chain containing 196 amino acids (21-191) and having a molecular mass of 21.8 kDa.CD27 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionCD27 belongs to the TNF-receptor superfamily. CD27 is necessary for initiation and long-term maintenance of T cell immunity. CD27 binds to ligand CD70, and has a crucial role in regulating B-cell activation and immunoglobulin synthesis. The CD27 receptor transduces signals which result in the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to the CD27 receptor and is believed to have a significant role in the apoptosis induced by CD27.
SynonymsTumor Necrosis Factor Receptor Superfamily Member 7,T-Cell Activation Antigen CD27, CD27 Molecule, CD27 Antigen,T Cell Activation Antigen S152, CD27L Receptor, TNFRSF7, S152, Tp55, T14.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CD27 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMTPAPK
SCPERHYWAQ
GKLCCQMCEP
GTFLVKDCDQ
HRKAAQCDPC
IPGVSFSPDH
HTRPHCESCR
HCNSGLLVRN
CTITANAECA
CRNGWQCRDK
ECTECDPLPN
PSLTARSSQA
LSPHPQPTHL
PYVSEMLEAR
TAGHMQTLAD
FRQLPARTLS
THWPPQRSLC
SSDFIR
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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