CD30 Human-CD Antigens

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CD30 Human

Qty


Total
$65
Catalog #
PRPS-1376
Size
Description
CD30 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 384 amino acids (19-379a.a.) and having a molecular mass of 40.8kDa. CD30 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTumor necrosis factor receptor superfamily member 8 (CD30) is a member of the TNF-receptor superfamily. CD30 is expressed by activated (not by resting) T and B cells. CD30 interacts with TRAF2 and TRAF5 which mediate the signal transduction that leads to the activation of NF-kappaB. CD30 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
SynonymsCD30, D1S166E, KI-1, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, TNFRSF8.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationCD30 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSFPQDRPF
EDTCHGNPSH
YYDKAVRRCC
YRCPMGLFPT
QQCPQRPTDC
RKQCEPDYYL
DEADRCTACV
TCSRDDLVEK
TPCAWNSSRV
CECRPGMFCS
TSAVNSCARC
FFHSVCPAGM
IVKFPGTAQK
NTVCEPASPG
VSPACASPEN
CKEPSSGTIP
QAKPTPVSPA
TSSASTMPVR
GGTRLAQEAA
SKLTRAPDSP
SSVGRPSSDP
GL
PurityGreater than 85% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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