CD68 Human-CD Antigens

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CD68 Human

Qty


Total
$65
Catalog #
PRPS-1216
Size
Description
CD68 Human Recombinant produced in E. coli is a single polypeptide chain containing 323 amino acids (22-319) and having a molecular mass of 34.1 kDa.CD68 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionCD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
SynonymsMacrosialin, Gp110, CD68 antigen, CD68, SCARD1, DKFZp686M18236.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CD68 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1M Urea and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHPLHHH
SSGLVPRGSH
MGSHMNDCPH
KKSATLLPSF
TVTPTVTEST
GTTSHRTTKS
HKTTTHRTTT
TGTTSHGPTT
ATHNPTTTSH
GNVTVHPTSN
STATSQGPST
ATHSPATTSH
GNATVHPTSN
STATSPGFTS
SAHPEPPPPS
PSPSPTSKET
IGDYTWTNGS
QPCVHLQAQI
QIRVMYTTQG
GGEAWGISVL
NPNKTKVQGS
CEGAHPHLLL
SFPYGHLSFG
FM
PurityGreater than 85% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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