CDK2AP1 Human-Cyclin-Dependent Kinase

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CDK2AP1 Human

Qty


Total
$65
Catalog #
PKPS-369
Size
Description
CDK2AP1 Human Recombinant fused to 37 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 152 amino acids (1-115 a.a.)and having a molecular mass of 16.6 kDa. The CDK2AP1 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionCDK2AP1 is a CDK2-associated protein that negatively regulates CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP1 interacts with DNA polymerase alpha and mediates the phosphorylation of the large p180 subunit, which implicates the regulatory role in DNA replication during S phase of the cell cycle.
SynonymsCyclin-dependent kinase 2-associated protein 1, CDK2-associated protein 1, Putative oral cancer suppressor, Deleted in oral cancer 1, DOC-1, CDK2AP1, CDKAP1, DOC1, ST19, DORC1, p12DOC-1.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear colorless solution.
FormulationThe CDK2AP1 solution contains 20mM Tris-HCl pH-8, 0.1M NaCl and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceRGSHHHHHH
GMASMTGGQQ
MGRDLYDDDD
KDRWGSHMSY
KPNLAAHMPA
AALNAAGSVH
SPSTSMATSS
QYRQLLSDYG
PPSLGYTQGT
GNSQVPQSKY
AELLAIIEEL
GKEIRPTYAG
SKSAMERLKR
GIIHARGLVR
ECLAETERNA
RS.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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