CIB2 Human-Calcium and Integrin Binding

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CIB2 Human

Qty


Total
$65
Catalog #
PKPS-275
Size
Description
CIB2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 207 amino acids (1-187a.a.) and having a molecular mass of 23.8kDa (Molecular weight on SDS-PAGE will appear higher). The CIB2 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionCIB2 is a member of the calcium and integrin-binding family.CIB2 is possibly a Ca2+-binding regulatory protein which interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs). In the skeletal muscle, CIB2 co-localizes with the integrin alpha7B subunit at the sarcolemma and at the neuromuscular and myotendinous junctions. CIB2 is closely related to CIB1.
SynonymsCalcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2, CIB2, KIP2.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CIB2 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT, 100mM NaCl and 1mM PMSF.
StabilityCIB2 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGNKQTIFTE
EQLDNYQDCT
FFNKKDILKL
HSRFYELAPN
LVPMDYRKSP
IVHVPMSLII
QMPELRENPF
KERIVAAFSE
DGEGNLTFND
FVDMFSVLCE
SAPRELKANY
AFKIYDFNTD
NFICKEDLEL
TLARLTKSEL
DEEEVVLVCD
KVIEEADLDG
DGKLGFADFE
DMIAKAPDFL
STFHIRI.
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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