CRADD Human-Other

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CRADD Human

Qty


Total
$65
Catalog #
PRPS-472
Size
Description
CRADD Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 219 amino acids (1-199) and having a molecular mass of 24.9 kDa. CRADD is fused to a 20 amino acids His-Tag at N-terminus.
Additional Information
IntroductionCRADD is a 22kDa, widely-expressed cytosolic adaptor/signaling protein that induces cell apoptosis/cell death in numerous tissues. CRADD is a death domain (CARD) that recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes TNFR1A, RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
SynonymsRAIDD, MGC9163, CRADD, Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CASP2 and RIPK1 domain containing adaptor with death domain.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CRADD protein solution (1mg/ml) contains 20mM Tris-HCl pH-8 and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MEARDKQVLR
SLRLELGAEV
LVEGLVLQYL
YQEGILTENH
IQEINAQTTG
LRKTMLMLDI
LPSRGPKAFD
TFLDSLQEFP
WVREKLKKAR
EEAMTDLPAG
DRLTGIPSHI
LNSSPSDRQI
NQLAQRLGPE
WEPMVLSLGL
SQTDIYRCKA
NHPHNVQSQV
VEAFIRWRQR
FGKQATFQSL
HNGLRAVEVD
PSLLLHMLE.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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