The E.coli derived recombinant 15kDa protein is genetically engineered peptide which is derived from Dengue Type-2 envelope III domain immunodeterminant regions. The expressed dengue envelope Type-2 III domain covers domain III region and is fused with a 6 His Tag at C-terminus. This peptide is particularly important for diagnostic and vaccine development as it contains multiple serotypes, neutralizing epitopes and receptor binding domain.
Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
Phosphate buffered saline pH 7.4.
Dengue Envelope-ST2 D-III althoµgh stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.