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Introduction | EDF1 controls endothelial cell differentiation. EDF1 has a role as a bridging protein that interconnects regulatory proteins and the basal transcriptional machinery, thus modulating the transcription of genes that take part in endothelial differentiation. EDF1 binds calmodulin throµgh its IQ domain and controls nitric oxide synthase activity via calmodulin sequestration in the cytoplasm. EDF1 is localized in adult liver, heart, adipose tissues, intestine and pancreas. |
Synonyms | EDF-1, MBF1, Multiprotein-bridging factor 1. |
Source | Escherichia Coli. |
Physical Appearance | Sterile filtered colorless solution. |
Formulation | 0.5 mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.1M NaCl & 10% glycerol. |
Stability | EDF1 Human althoµgh stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles. |
Amino Acid Sequence | MAESDWDTVT VLRKKGPTAA QAKSKQAILA AQRRGEDVET SKKWAAGQNK QHSITKNTAK LDRETEELHH DRVTLEVGKV IQQGRQSKGL TQKDLATKIN EKPQVIADYE SGRAIPNNQV LGKIERAIGL KLRGKDIGKP IEKGPRAKLE HHHHHH. |
Purity | Greater than 90.0% as determined by SDS-PAGE. |
Usage | NeoScientific''s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
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