FGF-18 Rat-Fibroblast Growth Factor

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FGF-18 Rat

Qty


Total
$65
Catalog #
CYPS-183
Size
Description
FGF18 Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 21.0kDa.The FGF 18 Rat is purified by proprietary chromatographic techniques.
Additional Information
IntroductionFibroblast growth factor 18 (FGF18) is a member of the large FGF family which has at least 23 members. FGF18 is a heparin binding growth factor with a core 120 amino acid FGF domain which allows for a common tertiary structure. FGFs are expressed in the course of the embryonic development and in restricted adult tissues. FGF-18 is an indispensable regulator of long bone and calvarial development. FGF-18 signals via FGFR 1c, 2c, 3c, and 4.
SynonymsFibroblast growth factor 18, FGF-18, zFGF5, Fgf18, D130055P09Rik.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationLyophilized from a 0.2um filtered concentrated solution in PBS, pH 7.4.
SolubilityIt is recommended to reconstitute the lyophilized FGF 18 in sterile 18M?-cm H2O not less than 100
StabilityLyophilized FGF 18 Rat althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF 18 Rat should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Amino Acid SequenceEENVDFRIHV
ENQTRARDDV
SRKQLRLYQL
YSRTSGKHIQ
VLGRRISARG
EDGDKYAQLL
VETDTFGSQV
RIKGKETEFY
LCMNRKGKLV
GKPDGTSKEC
VFIEKVLENN
YTALMSAKYS
GWYVGFTKKG
RPRKGPKTRE
NQQDVHFMKR
YPKGQTELQK
PFKYTTVTKR
SRRIRPTHPG
PurityGreater than 95.0% as determined by SDS-PAGE and HPLC analyses.
Biological ActivityThe ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ? 0.5ng/ml, corresponding to a specific activity of ? 2.0
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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