GPBB Human-Phosphorylase

our services
our products
Quotations & Ordering:

For quotations, please use our online quotation form, and you may also contact us by


+1-617.299.7367 (Int’l)


+1-617.299.7367 (Int’l)

Our customer service representatives are available 24 hours, Monday through Friday to assist you.

GPBB Human


Catalog #
Glycogen Phosphorylase Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain. The Human GPBB mature chain: 2 - 843 aa; that is a total of 842 aa having a molecular mass of 96695.96 Dalton. The theoretical pI is 6.40.The GPBB is purified by proprietary chromatographic techniques.
Additional Information
IntroductionGlycogen phosphorylase is one of the phosphorylaseenzymes(EC2.4.1.1). It breaks up glycogeninto glucosesubunits. Glycogenis left with one less glucosemolecule, and the free glucosemolecule is in the form of glucose-1-phosphate. In order to be used for metabolism, it must be converted to glucose-6-phosphateby the enzyme phosphoglucomutase.Glycogen phosphorylase can only act on linearchainsof glycogen(a 1-4 glycosidic linkage). Its work will immediately come to a halt four residues away from a 1-6 branch(which are exceedingly common in glycogen). In these situations, a debranching enzymeis necessary, which will straighten out the chain in that area. Additionally, an alpha 1-6 glucosidaseenzymeis required to break the remaining 1-6 residue that remains in the new linear chain. After all this is done, glycogen phosphorylase can continue.An insulinstimulated enzyme known as phosphoprotein phosphatase(PP-1) inactivates glycogen phosphorylase to prevent glycogen break up.GPBB - a sensitive marker for the AMI diagnosis within 4 hours after the onset of chest pain. It has also been shown that GPBB is increased in a considerable proportion of AMI patients within 2-3 hours from chest pain onset. GPBB is increased early in patients with unstable angina. GPBB can also be a sensitive marker for the detection of peri-operative myocardial ischaemia and infarction in patients undergoing coronary artery bypass grafting.
SynonymsGlycogen phosphorylase brain form, EC, GPBB, MGC9213, PYGB.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colourless liquid formualtion.
FormulationEach mg of protein contains 50% glycerol.
StabilityGPBB althoµgh stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.
PurityGreater than 85.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
ApplicationsImmunoassays and western blot.




Neo Scientific welcomes feedback from its customers.

If you have used an our product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information.

If you have any additional inquiries please email technical services at

Thank you for your support.



Custom Monoclonal Antibody
MassAb Technologies
Free Trial Custom Polyclonal Antibody
You will receive free purified antibodies for validation
Custom Peptides Synthesis

Start from $40/each

new technologies

Optimized for enhanced
expression levels
XPromoter 2.0
E.coli/insect cells/293 & CHO

3 in 1 expression system
MassAb Technologies

Cover All Epitopes