HIV-1 Protease-HIV

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HIV-1 Protease

Qty


Total
$65
Catalog #
HIPS-008
Size
Description
HIV-1 protease is an active homodimer having a molecular mass of 21.6kDa (each monomer of 99 amino acids is 10.8kDa).
Additional Information
IntroductionHIV-1 protease is very significant in the life cycle of the HIV virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytycaly released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure.
SynonymsNULL
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless clear solution.
FormulationThe HIV-1 Protease solution (0.25mg/1ml) is formulated in 20mM acetate, 200mM NaCl, 1mM EDTA, 0.5mM DTT, pH5.0 and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
UsageNeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Storage20mM HEPES, pH7.0 and 10% Glycerol.
Background

N/A

Protocol

N/A

MSDS
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