HMGN1 Human-High-Mobility Group

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HMGN1 Human

Qty


Total
$65
Catalog #
PRPS-828
Size
Description
HMGN1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 108 amino acids (1-100 a.a.) and having a molecular mass of 11.7 kDa. HMGN1 protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography.
Additional Information
IntroductionHMGN1 binds to the inner side of the nucleosomal DNA therefore changing the interaction between the DNA and the histone octamer. HMGN1 participates in the development which maintains transcribable genes in an exceptional chromatin conformation. HMGN1 inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2.
SynonymsHMG14, GC104230, High-Mobility Group Nucleosome Binding Domain 1.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationHMGN1 protein solution (0.5mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl, 0.1mM PMSF & 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMPKRKVSSAE
GAAKEEPKRR
SARLSAKPPA
KVEAKPKKAA
AKDKSSDKKV
QTKGKRGAKG
KQAEVANQET
KEDLPAENGE
TKTEESPASD
EAGEKEAKSD
LEHHHHHH.
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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