HSPA9 Human-Heat Shock Protein

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HSPA9 Human

Qty


Total
$65
Catalog #
HYPS-030
Size
Description
Recombinant Human HSPA9 produced in E.Coli is a single,non-glycosylated polypeptide chain containing 654 amino acids (47-679) and having a molecular mass of 71 kDa.HSP9A is expressed with a 20 amino acid His tag fused at N-Terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionHSPA9 is part of the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members that are also called heat-shock cognate proteins. HSPA9 encodes a heat-shock cognate protein that is involved in the control of cell proliferation and acts as a chaperone. HSPA9 was restricted to chromosome 5, band q31, a region that is often deleted in myeloid leukemias and myelodysplasia (MDS), making it a candidate tumor suppressor gene, which is consistent with the biological function of its murine homologue. HSPA9 supresses nuclear translocation, transcriptional activation, and control of centrosome-duplication functions of p53.
SynonymsMortalin, GRP75, MOT2, GSPA9B, PBP74, MOT-2, MTHSP75, Stress-70 protein mitochondrial, 75 kDa glucose-regulated protein, GRP 75, Heat shock 70 kDa protein 9, Peptide-binding protein 74, MOT, HSPA9, HSPA9B, CSA, MGC4500.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationThe HSPA9 protein solution contains 20mM Tris-HCl, pH-8, 10% glycerol and 0.5mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MASEAIKGAV
VGIDLGTTNS
CVAVMEGKQA
KVLENAEGAR
TTPSVVAFTA
DGERLVGMPA
KRQAVTNPNN
TFYATKRLIG
RRYDDPEVQK
DIKNVPFKIV
RASNGDAWVE
AHGKLYSPSQ
IGAFVLMKMK
ETAENYLGHT
AKNAVITVPA
YFNDSQRQAT
KDAGQISGLN
VLRVINEPTA
AALAYGLDKS
EDKVIAVYDL
GGGTFDISIL
EI
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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