IGF1 N15 Human-Insulin-Like Growth Factor

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IGF1 N15 Human

Qty


Total
$65
Catalog #
CYPS-135
Size
Description
IGF1 N15 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 70 amino acids and having a molecular mass of 7.73kDa.The IGF1 N15 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionThe somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted throµgh a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daµghaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003).
SynonymsSomatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationIGF1 N15 protein was lyophilized from a 0.2
SolubilityIt is recommended to reconstitute the lyophilized IGF1 N15 in sterile 18M?-cm H2O not less than 100
StabilityLyophilized IGF1 N15 althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGF1 N15 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceGPETLCGAEL
VDALQFVCGD
RGFYFNKPTG
YGSSSRRAPQ
TGIVDECCFR
SCDLRRLEMY
CAPLKPAKSA
PurityGreater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine BALB/C 3T3 cells is less than 1.0 ng/ml, corresponding to a specific activity of ? 1
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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