KGF 2 His Human-Keratinocyte Growth Factor

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KGF 2 His Human

Qty


Total
$65
Catalog #
CYPS-136
Size
Description
KGF 2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 196 amino acids (38-208) and having a molecular mass of 22.0kDa.KGF 2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionKGF-2 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of sµggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
SynonymsFGFA, FGF10, FGF-10, KGF-2, Fibroblast growth factor 10.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe KGF 2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl 2mM DTT, 2mM EDTA and 50% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMQALGQ
DMVSPEATNS
SSSSFSSPSS
AGRHVRSYNH
LQGDVRWRKL
FSFTKYFLKI
EKNGKVSGTK
KENCPYSILE
ITSVEIGVVA
VKAINSNYYL
AMNKKGKLYG
SKEFNNDCKL
KERIEENGYN
TYASFNWQHN
GRQMYVALNG
KGAPRRGQKT
RRKNTSAHFL
PMVVHS
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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