KLK5 Human-Kallikrein

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KLK5 Human

Qty


Total
$65
Catalog #
ENPS-637
Size
Description
KLK5 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 252 amino acids (67-293) and having a molecular mass of 27.8kDa.KLK5 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionKallikrein-5 (KLK5) is a member of the serine protease family of proteolytic enzymes. KLK5 is expressed in various tissues including the salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, thyroid, and trachea. KLK5 expression is up-regulated by estrogens and progestins. KLK5 is secreted and may be involved in desquamation in the epidermis. Kallikreins which are a subgroup of serine proteases, have distinct physiological functions. Many kallikreins are associated with carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK5 gene is one of the 15 kallikrein subfamily members located in a cluster on chromosome 19.
SynonymsKallikrein-5, Kallikrein-like protein 2, KLK-L2, Stratum corneum tryptic enzyme, KLK5, SCTE, UNQ570/PRO1132, KLKL2.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe KLK5 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMIINGS
DCDMHTQPWQ
AALLLRPNQL
YCGAVLVHPQ
WLLTAAHCRK
KVFRVRLGHY
SLSPVYESGQ
QMFQGVKSIP
HPGYSHPGHS
NDLMLIKLNR
RIRPTKDVRP
INVSSHCPSA
GTKCLVSGWG
TTKSPQVHFP
KVLQCLNISV
LSQKRCEDAY
PRQIDDTMFC
AGDKAGRDSC
QGDSGGPVVC
NGSLQGLVSW
GDYPCARPNR
PG
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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