MAGEA5 Human-Melanoma Antigen Family A

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MAGEA5 Human

Qty


Total
$65
Catalog #
PRPS-1077
Size
Description
MAGEA5 Human Recombinant produced in E. coli is a single polypeptide chain containing 148 amino acids (1-124) and having a molecular mass of 15.6kDa.MAGEA5 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionMAGEA5 belongs to the MAGEA gene family which encodes proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes are variable, which signify that the presence of this gene family enables the same role to be expressed under diverse transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They are associated with several hereditary disorders, like dyskeratosis congenita. MAGEA5 gene encodes a protein which is C-terminally truncated compared to other family members, and can be alternatively interpreted to be a pseudogene.
SynonymsMelanoma antigen family A 5, Cancer/testis antigen 1.5, CT1.5, cancer/testis antigen family 1 member 5, MAGE-5 (5a/5b) antigen, MAGEA4, MGC129526.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe MAGEA5 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1mM PMSF and 20% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMSLEQK
SQHCKPEEGL
DTQEEALGLV
GVQAATTEEQ
EAVSSSSPLV
PGTLGEVPAA
GSPGPLKSPQ
GASAIPTAID
FTLWRQSIKG
SSNQEEEGPS
TSPDPESVFR
AALSKKVADL
IHFLLLKY
PurityGreater than 85% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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