MAPKSP1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (1-124a.a.) and having a molecular mass of 15.8kDa.MAPKSP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
MAPKSP1 is a scaffold protein which operates in the extracellular signal-regulated kinase (ERK) cascade. MAPKSP1 protein is restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.
MAPBP, MP1, MAPK Scaffold Protein 1, Interacting Protein 1, MEK binding partner 1, Mitogen-Activated Protein Kinase kinase 1.
Sterile Filtered clear solution.
The MAPKSP1 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 5mM DTT, 100mM NaCl and 20% glycerol.