MAPRE1 Human-Microtubule-Associated Protein

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MAPRE1 Human

Qty


Total
$65
Catalog #
PRPS-065
Size
Description
MAPRE1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 288 amino acids (1-268 a.a.) and having a molecular mass of 32.2kDa. The MAPRE1 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionMAPRE1 (EB1) is a member of the intermediate/early gene family. MAPRE1 was first identified by its binding to the APC protein, which is often mutated in familial and sporadic, forms of colorectal cancer. MAPRE1 localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, MAPRE1 is associated with the centrosomes and spindle microtubules. MAPRE1 is involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes.
SynonymsMicrotubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1, EB1, MAPRE1, MGC117374, MGC129946.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe MAPRE1 solution (0.5 mg/ml) 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAVNVYSTSV
TSDNLSRHDM
LAWINESLQL
NLTKIEQLCS
GAAYCQFMDM
LFPGSIALKK
VKFQAKLEHE
YIQNFKILQA
GFKRMGVDKI
IPVDKLVKGK
FQDNFEFVQW
FKKFFDANYD
GKDYDPVAAR
QGQETAVAPS
LVAPALNKPK
KPLTSSSAAP
QRPISTQRTA
AAPKAGPGVV
RKNPGVGNGD
DEAAELMQQV
NVLKLTVEDL
EK
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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