MIF Human His N-Macrophage Migration Inhibitor

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MIF Human His N

Qty


Total
$65
Catalog #
CYPS-438
Size
Description
MIF human Recombinant, fused to His-tag at N-terminus, was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques. Macrophage Inducing Factor Human Recombinant is a single, non-glycosylated, polypeptide chain having amino acids from 1-114 and having a molecular mass of 16.6 kDa.
Additional Information
IntroductionThe cytokine Macrophage Migration Inhibitor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.
SynonymsPhenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, MMIF, MIF.
SourceEscherichia Coli.
Formulation1mg/ml solution containing PBS pH-7.4.
StabilityLiquid MIF althoµgh stable 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
Amino Acid SequenceMRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMPMFIVNTNV
PRASVPDGFL
SELTQQLAQA
TGKPPQYIAV
HVVPDQLMAF
GGSSEPCALC
LHSIGKIGGA
QNRSYSKLLC
GLLAERLRIS
PDRVYINYYD
MNAANVGWNN
STFA.
PurityGreater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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