MIP-1 Gamma Mouse-MIP

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MIP-1 Gamma Mouse

Qty


Total
$65
Catalog #
CHPS-264
Size
Description
MIP-1 gamma Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 101 amino acids and having a molecular mass of 11.6 kDa. The MIP-1 gamma is purified by proprietary chromatographic techniques.
Additional Information
IntroductionMouse MIP-1 gamma is 75% identical in its amino acid compostion as compared to the rat specie. MIP-1 gamma is a CC chemokine localized in murine blood and a widespread range of murine tissues, without having an identified human homolog. MIP-1 gamma signals throµgh the CCR1 receptor. MIP-1 gamma chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1 gamma has six cysteines including the four highly conserved cysteine residues present in CC chemokines.
SynonymsCCL9/10, MRP2, CCF18.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationThe MIP-1 gamma was lyophilized from 1xPBS solution pH-7.4.
SolubilityIt is recommended to reconstitute the lyophilized MIP-1 gamma in sterile 18M?-cm H2O not less than 100
StabilityLyophilized MIP-1 gamma althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL9/10 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceQITHATETKE
VQSSLKAQQG
LEIEMFHMGF
QDSSDCCLSY
NSRIQCSRFI
GYFPTSGGCT
RPGIIFISKR
GFQVCANPSD
RRVQRCIERL
EQNSQPRTYK
Q.
PurityGreater than 97.0% as determined by (a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Biological ActivityDefined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10 ng/ml, corresponding to a Specific Activity of 10,000-100,000IU/mg.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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