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Introduction | N-myc-interactor belongs to the oncogene Myc family which has a significant part in cell proliferation, differentiation, and neoplastic transformation. In Addition, NMI cooperates with all STATs except STAT2 and aµgments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA is expressed in small quantities in all human fetal and adult tissues tested except brain and but in large quantities in cancer cell line-myeloid leukemias. |
Synonyms | N-myc (and STAT) Interactor. |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered clear solution. |
Formulation | The NMI protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0)1mM DTT and 20% glycerol. |
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MEADKDDTQQ ILKEHSPDEF IKDEQNKGLI DEITKKNIQLK KEIQKLETE LQEATKEFQI KEDIPETKMK FLSVETPEND SQLSNISCSF QVSSKVPYEI QKGQALITFE KEEVAQNVVS MSKHHVQIKDV NLEVTAKPV PLNSGVRFQV YVEVSKMKIN VTEIPDTLRE DQMRDKLELS FSKSRNGGGE VDRVDYDRQS GSAVITFVEI GV |
Purity | Greater than 90% as determined by SDS-PAGE. |
Usage | NeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles. |
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