PARD6B Human-Other

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PARD6B Human

Qty


Total
$65
Catalog #
PRPS-1314
Size
Description
PARD6B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 395 amino acids (1-372) and having a molecular mass of 43.6kDa.PARD6B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionPartitioning defective 6 homolog beta (PARD6B) belongs to the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is crucial for the development of multicellular organisms. PARD (partitioning-defective) proteins have central roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. PARD6B is expressed in pancreas and in both the adult and the fetal kidney, and is weakly expressed in the placenta and the lung.
SynonymsPartitioning defective 6 homolog beta, PAR-6 beta, PAR-6B, PARD6B, PAR6B.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe PARD6B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea, 20% glycerol and 0.2M NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMNRSHRH
GAGSGCLGTM
EVKSKFGAEF
RRFSLERSKP
GKFEEFYGLL
QHVHKIPNVD
VLVGYADIHG
DLLPINNDDN
YHKAVSTANP
LLRIFIQKKE
EADYSAFGTD
TLIKKKNVLT
NVLRPDNHRK
KPHIVISMPQ
DFRPVSSIID
VDILPETHRR
VRLYKYGTEK
PLGFYIRDGS
SVRVTPHGLE
KVPGIFISRL
VPGGLAQSTG
LL
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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