PF 4 Mouse-Platelet Factor-4 (CXCL4)

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PF 4 Mouse

Qty


Total
$65
Catalog #
CHPS-252
Size
Description
CXCL4 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 76 amino acids and having a molecular mass of 8.2kDa.
Additional Information
IntroductionPlatelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
SynonymsCXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered white lyophilized powder.
FormulationThe Mouse CXCL4 protein was lyophilized from a 0.2
SolubilityIt is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
StabilityLyophilized CXCL4 Mouse Recombinant althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse CXCL4 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Amino Acid SequenceVTSAGPEESD
GDLSCVCVKT
ISSGIHLKHI
TSLEVIKAGR
HCAVPQLIAT
LKNGRKICLD
RQAPLYKKVI
KKILES.
PurityGreater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs,agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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