PIR Human-Other

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PIR Human

Qty


Total
$65
Catalog #
PRPS-1047
Size
Description
PIR Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 310 amino acids (1-290 a.a.) and having a molecular mass of 34.3kDa.PIR is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionPirin (PIR) which belongs to the cupin superfamily, is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Pirin may function as a transcriptional cofactor and is involved in the regulation of DNA transcription and replication, as a result of interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein.
SynonymsPirin, Probable quercetin 2,3-dioxygenase PIR, Probable quercetinase, PIR.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationPIR protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSSKKVTLS
VLSREQSEGV
GARVRRSIGR
PELKNLDPFL
LFDEFKGGRP
GGFPDHPHRG
FETVSYLLEG
GSMAHEDFCG
HTGKMNPGDL
QWMTAGRGIL
HAEMPCSEEP
AHGLQLWVNL
RSSEKMVEPQ
YQELKSEEIP
KPSKDGVTVA
VISGEALGIK
SKVYTRTPTL
YLDFKLDPGA
KHSQPIPKGW
TSFIYTISGD
VYIGPDDAQQ
KI
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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