RAB23 Human-Member RAS Oncogene Family

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RAB23 Human

Qty


Total
$65
Catalog #
PRPS-984
Size
Description
RAB23 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 254 amino acids (1-234) and having a molecular mass of 28.5 kDa.RAB23 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionRAB23 belongs to the Rab family of proteins and is restricted to the cytoplasmic side of the cell membrane. RAB23 takes part in intracellular protein transportation and signal transduction facilitated by small GTPases. RAB23 is a vital negative regulator of the Sonic hedgehog signaling pathway. Alterations in the gene encoding RAB23 are the origin for Carpenter syndrome a disorder which can cause obesity, cardiac defects, polysyndactyly and craniosynostosis.
SynonymsRAB23 member RAS oncogene family, HSPC137, RAB family small GTP binding protein RAB 23, ras-related protein Rab-23.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe RAB23 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1mM PMSF and 30% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MLEEDMEVAI
KMVVVGNGAV
GKSSMIQRYC
KGIFTKDYKK
TIGVDFLERQ
IQVNDEDVRL
MLWDTAGQEE
FDAITKAYYR
GAQACVLVFS
TTDRESFEAV
SSWREKVVAE
VGDIPTVLVQ
NKIDLLDDSC
IKNEEAEALA
KRLKLRFYRT
SVKEDLNVNE
VFKYLAEKYL
QKLKQQIAED
PELTHSSSNK
IGVFNTSGGS
HSGQNSGTLN
GG
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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