RAB27A Human-Member RAS Oncogene Family

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RAB27A Human

Qty


Total
$65
Catalog #
PRPS-832
Size
Description
RAB27A Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 241 amino acids(1-221a.a.) and having a molecular mass of 27 kDa. RAB27A protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
Additional Information
IntroductionRAB27A is part of the small GTPase superfamily, Rab family. RAB27A is membrane-bound and participates in protein transport and small GTPase mediated signal transduction. Mutations in this RAB27A are associated with Griscelli syndrome type 2. RAB27A is involved in cytotoxic granule exocytosis in lymphocytes.RAB27A is necessary for both granule maturation and granule docking and priming at the immunologic synapse.
SynonymsGS2, RAM, RAB27, GS2, HsT18676, MGC117246, RAB27A, member RAS oncogene family.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationRAB27A Human solution containing 20mM Trsi HCL pH-8, 1mM DTT, & 20% glycerol.
StabilityRAB27A Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSDGDYDYLI
KFLALGDSGV
GKTSVLYQYT
DGKFNSKFIT
TVGIDFREKR
VVYRASGPDG
ATGRGQRIHL
QLWDTAGQER
FRSLTTAFFR
DAMGFLLLFD
LTNEQSFLNV
RNWISQLQMH
AYCENPDIVL
CGNKSDLEDQ
RVVKEEEAIA
LAEKYGIPYF
ETSAANGTNI
SQAIEMLLDL
IMKRMERCVD
KSWIPEGVVR
SNGHASTDQL
SE
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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