RANBP1 Human-Other

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RANBP1 Human

Qty


Total
$65
Catalog #
PRPS-1071
Size
Description
RANBP1 Human Recombinant produced in E. coli is a single polypeptide chain containing 225 amino acids (1-201) and having a molecular mass of 25.8kDa.RANBP1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionRANBP1 is a member of a family of proteins which bind Ran GTPase. Ran GTPase is vital for cell cycle control, mRNA processing, nuclear transport, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. RANBP1 does not stimulate GTPase activity of RAN however RANBP1 does distinctly raise GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). Additionally, RANBP1 operates as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
SynonymsRAN binding protein 1, HTF9A, ran-specific GTPase-activating protein, RanBP1.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe RANBP1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMAAAKD
THEDHDTSTE
NTDESNHDPQ
FEPIVSLPEQ
EIKTLEEDEE
ELFKMRAKLF
RFASENDLPE
WKERGTGDVK
LLKHKEKGAI
RLLMRRDKTL
KICANHYITP
MMELKPNAGS
DRAWVWNTHA
DFADECPKPE
LLAIRFLNAE
NAQKFKTKFE
ECRKEIEERE
KKAGSGKNDH
AEKVAEKLEA
LSVKEETKED
AEEKQ
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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