RANGRF Human-Other

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RANGRF Human

Qty


Total
$65
Catalog #
PRPS-1156
Size
Description
RANGRF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-186 a.a) and having a molecular mass of 23kDa.RANGRF is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionRANGRF is a protein which acts as a guanine nucleotide release factor in mouse and regulates the expression and function of the Nav1.5 cardiac sodium channel in human. RANGRF also controls the intracellular trafficking of RAN. In cardiac cells, the RANGRF appears to regulate the cell surface localization of SCN5A.
SynonymsRan guanine nucleotide release factor, RanGNRF, Ran-binding protein MOG1, RANGRF, MOG1, HSPC165, HSPC236, MDS5.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationRANGRF protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.15M NaCl and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMEPTRD
CPLFGGAFSA
ILPMGAIDVS
DLRPVPDNQE
VFCHPVTDQS
LIVELLELQA
HVRGEAAARY
HFEDVGGVQG
ARAVHVESVQ
PLSLENLALR
GRCQEAWVLS
GKQQIAKENQ
QVAKDVTLHQ
ALLRLPQYQT
DLLLTFNQPP
PDNRSSLGPE
NLSPAPWSLG
DFEQLVTSLT
LHDPNIFGPQ.
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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