RASSF1A Human-Other

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RASSF1A Human

Qty


Total
$65
Catalog #
PRPS-1295
Size
Description
RASSF1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 376 amino acids (1-340 a.a.) and having a molecular mass of 42.9kDa. RASSF1A is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionRASSF1A protein is a potential tumor suppressor like the RAS effector proteins. Presence or absence expression of this gene has been related with the pathogenesis of a variety of cancers, which sµggests the tumor suppressor function of this RASSF1A gene. The inactivation of RASSF1A was found to be associated with the hypermethylation of its CpG-island promoter region. RASSF1A required for death receptor-dependent apoptosis.
Synonyms123F2, NORE2A, RASSF1, RDA32, REH3P21, Ras association domain-containing protein 1.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationRASSF1A protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0) 0.4M Urea and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMRGSHHHHHH
GMASMTGGQQ
MGRDLYDDDD
KDRWGSMSGE
PELIELRELA
PAGRAGKGRT
RLERANALRI
ARGTACNPTR
QLVPGRGHRF
QPAGPATHTW
CDLCGDFIWG
VVRKGLQCAH
CKFTCHYRCR
ALVCLDCCGP
RDLGWEPAVE
RDTNVDEPVE
WETPDLSQAE
IEQKIKEYNA
QINSNLFMSL
NKDGSYTGFI
KVQLKLVRPV
SVPSSKKPPS
LQDARRGPGR
GT
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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