RGN Human-Other

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RGN Human

Qty


Total
$65
Catalog #
PRPS-922
Size
Description
RGN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 319 amino acids (1-299 a.a.) and having a molecular mass of 35.4kDa.RGN is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionRegucalcin (RGN) is a member of the SMP-30/CGR1 family. Regucalcin is a Ca (2+)-binding protein which does not contain EF-hand motif of Ca (2+)-binding domain. RGN has a critical role in the keep of intracellular Ca2+ homeostasis due to activating of Ca2+ pump enzymes in the plasma membrane (basolateral membrane), microsomes (endoplasmic reticulum) and mitochondria of many cells. Moreover, RGN plays a multifunctional role in the regulation of cell functions in the liver, kidney cortex, heart and brain and a suppressor protein for cell signaling systems in many cell types.
SynonymsRegucalcin, RC, Gluconolactonase, GNL, Senescence marker protein 30, SMP-30, RGN, SMP30.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationRGN protein solution (0.5mg/ml) containing 20mM Tris-HCl, pH8.0, 2M Urea and 20% Glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSSIKIECVL
PENCRCGESP
VWEEVSNSLL
FVDIPAKKVC
RWDSFTKQVQ
RVTMDAPVSS
VALRQSGGYV
ATIGTKFCAL
NWKEQSAVVL
ATVDNDKKNN
RFNDGKVDPA
GRYFAGTMAE
ETAPAVLERH
QGALYSLFPD
HHVKKYFDQV
DISNGLDWSL
DHKIFYYIDS
LSYSVDAFDY
DLQTGQISNR
RSVYKLEKEE
QIPDGMCIDA
EG
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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