RP9 Human-Other

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RP9 Human

Qty


Total
$65
Catalog #
PRPS-1321
Size
Description
RP9 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 178 amino acids (1-155 a.a.) and having a molecular mass of 20.7kDa.RP9 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionRetinitis pigmentosa 9 (RP9) is assumed to be a target protein for the PIM1 kinase. The RP9 protein may have some roles in B-cell proliferation in association with PIM1. RP9 can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase. RP9 localizes in nuclear speckles containing the splicing factors, and has a part in pre-mRNA splicing. RP9 gene mutations result in autosomal dominant retinitis pigmentosa-9.
SynonymsRetinitis pigmentosa 9 protein, Pim-1-associated protein, PAP-1, RP9.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationRP9 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMSSRPGR
EDVGAAGARR
PREPPEQELQ
RRREQKRRRH
DAQQLQQLKH
LESFYEKPPP
GLIKEDETKP
EDCIPDVPGN
EHAREFLAHA
PTKGLWMPLG
KEVKVMQCWR
CKRYGHRTGD
KECPFFIKGN
QKLEQFRVAH
EDPMYDIIRD
NKRHEKDV.
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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