RUNX3 Human-Other

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RUNX3 Human

Qty


Total
$65
Catalog #
PRPS-843
Size
Description
RUNX3 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids (53-186 a.a.) and having a molecular mass of 17.1 kDa. The RUNX3 is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionRUNX3 is part of the RUNX family that mediates the expression of genes which participate in cellular differentiation and cell cycle progression. RUNX3 heterodimer and the beta subunit form a complex that binds to the core DNA sequence 5''-PYGPYGGT-3'' found in several enhancers and promoters, and can either activate or suppress transcription. RUNX3 interacts with additional transcription factors. RUNX3 is a good candidate for gastric cancer tumor suppressor diagnosis.
SynonymsAML2, CBFA3, PEBP2aC, PEBP2A3, FLJ34510, MGC16070, RUNX3, Oncogene AML-2, Runt-related transcription factor 3, Core-binding factor subunit alpha-3, Acute myeloid leukemia 2 protein, Polyomavirus enhancer-binding protein 2 alpha C subunit, SL3-3 enhancer f
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationRUNX3 Human solution containing 20mM Tris HCL pH-8, 0.1M NaCl, & 20% glycerol.
StabilityRUNX3 Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MRSMVDVLAD
HAGELVRTDS
PNFLCSVLPS
HWRCNKTLPV
AFKVVALGDV
PDGTVVTVMA
GNDENYSAEL
RNASAVMKNQ
VARFNDLRFV
GRSGRGKSFT
LTITVFTNPT
QVATYHRAIK
VTVDGPREPR
RHRQK.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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