SHC1 Human-Other

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SHC1 Human

Qty


Total
$65
Catalog #
PRPS-890
Size
Description
SHC1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 494 amino acids (1-474) and having a molecular mass of 53.8 kDa.The SHC1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionSHC1 is a member of the SH2 domain family. SHC1 is vital to the regulation of apoptosis and drµg resistance in mammalian cells. SHC1 is a signaling adapter which links activated growth factor receptors to signaling pathway. SHC1 is found in neural stem cells but not in mature neurons.
SynonymsSHC (Src homology 2 domain containing) transforming protein 1, SHC, SHCA, SH2 domain protein C1, SHC-transforming protein 3, SHC-transforming protein A, FLJ26504, p66.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationSHC1 protein (1mg/ml) is supplied in 20mM Tris-HCl, pH-8, 2mM DTT, 200mM NaCl, 0.1mM PMSF and 20% Glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MNKLSGGGGR
RTRVEGGQLG
GEEWTRHGSF
VNKPTRGWLH
PNDKVMGPGV
SYLVRYMGCV
EVLQSMRALD
FNTRTQVTRE
AISLVCEAVP
GAKGATRRRK
PCSRPLSSIL
GRSNLKFAGM
PITLTVSTSS
LNLMAADCKQ
IIANHHMQSI
SFASGGDPDT
AEYVAYVAKD
PVNQRACHIL
ECPEGLAQDV
ISTIGQAFEL
RFKQYLRNPP
KL
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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