Stratifin Human-14-3-3

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Stratifin Human

Qty


Total
$65
Catalog #
PKPS-364
Size
Description
Stratifin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 248 amino acids (1-248) and having a molecular mass of 27.7 kDa. Stratifin is purified by proprietary chromatographic techniques.
Additional Information
IntroductionStratifin is part of the 14-3-3 family. The 14-3-3 family of proteins plays an important regulatory function in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are 7 isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. Stratifin is an epithelial cell marker that functions as a tumor suppressor whose expression can be down regulated via methylation. Failure of Stratifin expression results in a defective G2/M phase checkpoint and results in epithelial and non-epithelial tumorigenesis.
Synonyms14-3-3 protein sigma, Epithelial cell marker protein 1, HME1, Stratifin, YWHAS, SFN, Stratifin.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationStratifin solution containing 20mM Tris-HCl pH-8, 50mM NaCl and 10% Glycerol.
StabilityStratifin Human Recombinant althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMERASLIQKA
KLAEQAERYE
DMAAFMKGAV
EKGEELSCEE
RNLLSVAYKN
VVGGQRAAWR
VLSSIEQKSN
EEGSEEKGPE
VREYREKVET
ELQGVCDTVL
GLLDSHLIKE
AGDAESRVFY
LKMKGDYYRY
LAEVATGDDK
KRIIDSARSA
YQEAMDISKK
EMPPTNPIRL
GLALNFSVFH
YEIANSPEEA
ISLAKTTFDE
AMADLHTLSE
DSYKDSTLIM
QLLRDNLTLW
TA
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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