SUFU Human-Other

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SUFU Human

Qty


Total
$65
Catalog #
PRPS-945
Size
Description
SUFU Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 504 amino acids (1-484 a.a.) and having a molecular mass of 56.1kDa.SUFU is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionSuppressor of fused homolog (SUFU) is a member of the SUFU family. SUFU is a negative regulator of the hedgehog signaling pathway. SUFU interacts with GLI1, GLI3 and PEX26. Defects in the SUFU gene are a cause of medulloblastoma.
SynonymsSuppressor of fused homolog, SUFUH, SUFU, UNQ650/PRO1280, SUFUXL, PRO1280.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationSUFU protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 10% glycerol and 50mM NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MAELRPSGAP
GPTAPPAPGP
TAPPAFASLF
PPGLHAIYGE
CRRLYPDQPN
PLQVTAIVKY
WLGGPDPLDY
VSMYRNVGSP
SANIPEHWHY
ISFGLSDLYG
DNRVHEFTGT
DGPSGFGFEL
TFRLKRETGE
SAPPTWPAEL
MQGLARYVFQ
SENTFCSGDH
VSWHSPLDNS
ESRIQHMLLT
EDPQMQPVQT
PFGVVTFLQI
VGVCTEELHS
AQ
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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