SULT2B1 Human Recombinant produced in E.Coli is a single, non-glycosylated,polypeptide chain containing 365 amino acids(1-365 a.a.) and having a molecular mass of 41.3 kDa. SULT2B1 protein is purified by standard chromatography.
SULT2B1 catalyzes the sulfate conjµgation of numerous hormones, neurotransmitters, drµgs and xenobiotic compounds. Sulfonation enhances the water solubility of molecules, and therefore their renal excretion, however it can also result in bioactivation to form active metabolites. SULT2B1b is localized in the cytosol and nuclei of human cells. SULT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and participates in cholesterol sulfation in human skin.
SULT2B1, HSST2, EC 188.8.131.52, Sulfotransferase 2B1, Hydroxysteroid sulfotransferase 2, ST2B1, Sulfotransferase family cytosolic 2B member 1.