Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion throµgh viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation throµgh genome reduction to the rich environment of mammalian tissue.
10mM Tris-HCl pH8.0, 1mM EDTA, 1mMDTT and 8M urea.
Treponema pallidum protein is >90% pure as determined by 10% PAGE (coomassie staining).
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Treponema pallidum is suitable for ELISA and Western blots, excellent antigen for detection of T. Pallidum with minimal specificity problems.
T.pallidum p41 althoµgh stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Treponema pallidum protein was purified by proprietary chromatographic technique.
Immunoreactive with sera of T.Pallidum infected individuals.