TANK Human-Other

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TANK Human

Qty


Total
$65
Catalog #
PRPS-1355
Size
Description
TANK Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 448 amino acids (1-425a.a) and having a molecular mass of 50.2kDa. TANK is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTRAF Family Member-Associated NFKB Activator (TANK) is located in the cytoplasm and binds Either TRAF1, TRAF2 or TRAF3. TANK is an inhibitor of TRAF function which regulates TRAF protein activity via sequestering TRAFs in a dormant position in the cytoplasm. Overexpression of TANK, inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and also inhibits LMP1-mediated NFkappa-B activation by blocking the connection of TRAF2 with LMP1.
SynonymsTRAF, TRAF2, TRAF-interacting protein, ITRAF.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationTANK protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
StabilityA2LD1 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMDKNIGE
QLNKAYEAFR
QACMDRDSAV
KELQQKTENY
EQRIREQQEQ
LSLQQTIIDK
LKSQLLLVNS
TQDNNYGCVP
LLEDSETRKN
NLTLDQPQDK
VISGIAREKL
PKVRRQEVSS
PRKETSARSL
GSPLLHERGN
IEKTFWDLKE
EFHKICMLAK
AQKDHLSKLN
IPDTATETQC
SVPIQCTDKT
DKQEALFKPQ
AKDDINRGAP
SI
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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