TFB1M Human-Other

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TFB1M Human

Qty


Total
$65
Catalog #
PRPS-910
Size
Description
TFB1M Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 340 amino acids (28-346 a.a.) and having a molecular mass of 38.8kDa.TFB1M is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTFB1M is a member of the methyltransferase superfamily. TFB1M is a dimethyltransferase which methylates mitochondrial 12S rRNA at the conserved stem loop. The TFB1M protein also is part of the basal mitochondrial transcription complex and is required for mitochondrial gene expression. TFB1M stimulates transcription independently of the methyltransferase activity.
SynonymsDimethyladenosine transferase 1 mitochondrial, Mitochondrial 12S rRNA dimethylase 1, Mitochondrial transcription factor B1, h-mtTFB, h-mtTFB1, hTFB1M, mtTFB1, S-adenosylmethionine-6-N'-N'-adenosyl(rRNA) dimethyltransferase 1, TFB1M, CGI-75, CGI75, mtTFB.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationTFB1M protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MQAAKQLSQN
FLLDLRLTDK
IVRKAGNLTN
AYVYEVGPGP
GGITRSILNA
DVAELLVVEK
DTRFIPGLQM
LSDAAPGKLR
IVHGDVLTFK
VEKAFSESLK
RPWEDDPPNV
HIIGNLPFSV
STPLIIKWLE
NISCRDGPFV
YGRTQMTLTF
QKEVAERLAA
NTGSKQRSRL
SVMAQYLCNV
RHIFTIPGQA
FVPKPEVDVG
VVHFTPLIQP
KI
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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