TMOD3 Human-Other

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TMOD3 Human

Qty


Total
$65
Catalog #
PRPS-1172
Size
Description
TMOD3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 376 amino acids (1-352 a.a) and having a molecular mass of 42kDa.TMOD3 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTropomodulin 3 (TMOD3) is a member of the tropomodulin family. TMOD3 prevents the elongation and depolymerization of the actin filaments at the pointed end. Actin cytoskeleton regulation by filament capping proteins is essential to many dynamic cellular functions. TMOD3 functions as a negative regulator of cell migration; nevertheless the processes behind its cellular functions are unknown. The Tmod/TM complex influences the formation of the short actin protofilament, which sequentially outlines the geometry of the membrane skeleton.
SynonymsTropomodulin-3, Ubiquitous tropomodulin, U-Tmod, TMOD3, UTMOD.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationTMOD3 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMALPFR
KDLEKYKDLD
EDELLGNLSE
TELKQLETVL
DDLDPENALL
PAGFRQKNQT
SKSTTGPFDR
EHLLSYLEKE
ALEHKDREDY
VPYTGEKKGK
IFIPKQKPVQ
TFTEEKVSLD
PELEEALTSA
SDTELCDLAA
ILGMHNLITN
TKFCNIMGSS
NGVDQEHFSN
VVKGEKILPV
FDEPPNPTNV
EESLKRTKEN
DAHLVEVNLN
NI
PurityGreater than 80.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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