TNNI1 Human-Cardiac Troponin

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TNNI1 Human

Qty


Total
$65
Catalog #
PRPS-1276
Size
Description
TNNI1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-187 a.a.) and having a molecular mass of 23.8kDa.TNNI1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTroponin I, (TNNI1) is a member of the troponin I family. Troponin complex has 3 subunits, TNNI1 known as the inhibitory Subunit which prevents the actin-myosin interactions and thus mediating striated muscle relaxation. TNNI1 combines with tropomyosin and regulates calcium sensitivity of striated muscles by structural modifications in actin-myosin complexes.
SynonymsDKFZp451O223, SSTNI, TNN1, Troponin I, slow skeletal muscle ,Troponin I, slow-twitch isoform.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationTNNI1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MPEVERKPKI
TASRKLLLKS
LMLAKAKECW
EQEHEEREAE
KVRYLAERIP
TLQTRGLSLS
ALQDLCRELH
AKVEVVDEER
YDIEAKCLHN
TREIKDLKLK
VMDLRGKFKR
PPLRRVRVSA
DAMLRALLGS
KHKVSMDLRA
NLKSVKKEDT
EKERPVEVGD
WRKNVEAMSG
MEGRKKMFDA
AKSPTSQ
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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