TNNT2 Human-Cardiac Troponin

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TNNT2 Human

Qty


Total
$65
Catalog #
PRPS-710
Size
Description
TNNT2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 305 amino acids (1-285 a.a.) and having a molecular mass of 36.4 kDa. The TNNT2 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionTNNT2 is the tropomyosin-binding subunit of the troponin complex, which is situated on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in TNNT2 gene are related with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. TNNT2 mutation takes part in hypertrophic cardiomyopathy.
SynonymsCMH2, RCM3, TnTC, cTnT, CMPD2, MGC3889, TNNT2, Troponin T- cardiac muscle, Cardiac muscle troponin T, troponin T type 2 (cardiac).
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe TNNT2 solution contains 20mM Tris pH-8 & 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSDIEEVVEE
YEEEEQEEAA
VEEQEEAAEE
DAEAEAETEE
TRAEEDEEEE
EAKEAEDGPM
EESKPKPRSF
MPNLVPPKIP
DGERVDFDDI
HRKRMEKDLN
ELQALIEAHF
ENRKKEEEEL
VSLKDRIERR
RAERAEQQRI
RNEREKERQN
RLAEERARRE
EEENRRKAED
EARKKKALSN
MMHFGGYIQK
TERKSGKRQT
EREKKKKILA
ER
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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