TREX2 Human-Nuclease

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TREX2 Human

Qty


Total
$65
Catalog #
ENPS-102
Size
Description
TREX2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 256 amino acids (1-236a.a.) and having a molecular mass of 28.0 kDa. TREX2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionTREX2 holds a 3-prime-to-5-prime exonuclease activity and eliminates mismatched, modified, fragmented, and normal nucleotides to produce the appropriate 3-prime termini for following steps in the DNA metabolic pathways. TREX2 has a role in DNA replication, repair, and recombination.
SynonymsThree Prime Repair Exonuclease 2, 3'-5' exonuclease TREX2 long form.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe TREX2 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 200mM NaCl, 5mM DTT and 30% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSEAPRAETF
VFLDLEATGL
PSVEPEIAEL
SLFAVHRSSL
ENPEHDESGA
LVLPRVLDKL
TLCMCPERPF
TAKASEITGL
SSEGLARCRK
AGFDGAVVRT
LQAFLSRQAG
PICLVAHNGF
DYDFPLLCAE
LRRLGARLPR
DTVCLDTLPA
LRGLDRAHSH
GTRARGRQGY
SLGSLFHRYF
RAEPSAAHSA
EGDVHTLLLI
FLHRAAELLA
WA
PurityGreater than 95% as determined by SDS-PAGE.
UsageNeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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